How to Increase Nitric Oxide Naturally

Nitric oxide may be a tiny molecule, but it plays an important role in blood vessel relaxation, blood flow, exercise, and cardiovascular function.

Your body can make nitric oxide naturally, but diet and everyday habits can affect how much is available.

Nitrate-rich foods, physical activity, and even the bacteria in your mouth can influence this process.

How to Increase Nitric Oxide Production

You do not necessarily need a nitric oxide supplement to support nitric oxide production. Several everyday habits can help.

1. Eat More Nitrate-Rich Vegetables

One of the simplest ways to support nitric oxide production is to eat more vegetables naturally rich in nitrate.

Good choices include:

  • Beetroot
  • Arugula
  • Spinach
  • Lettuce
  • Swiss chard
  • Celery
  • Other leafy greens

Nitrate from these foods can be converted by bacteria in your mouth into nitrite, which can then contribute to nitric oxide production. Leafy greens are among the richest dietary sources of nitrate.

You don’t need to eat large amounts of one particular vegetable. Instead, try adding a variety of nitrate-rich foods to your regular meals.

2. Exercise Regularly

Exercise is another powerful way to support your body’s nitric oxide system.

During physical activity, increased blood flow creates friction against the walls of your blood vessels. This stimulates the cells lining your vessels to produce more nitric oxide and may help them respond better to changes in blood flow.

Research suggests that exercise can increase nitric oxide and related nitrate/nitrite levels in the blood. This benefit was seen with both aerobic and high-intensity interval training, regardless of exercise duration or session length.

You don’t need intense workouts to get these benefits. Walking, cycling, swimming, running, resistance training, and other forms of regular physical activity can support vascular health.

The most important factor is consistency.

3. Give Your Oral Health Some Attention

This one is easy to overlook.

The bacteria living in your mouth play an important role in the nitrate-to-nitrite-to-nitric oxide pathway. When you eat nitrate-rich foods, these bacteria help convert nitrate into nitrite before it continues through the pathway.

Research suggests that disrupting the oral microbiome, including through certain antiseptic mouthwashes, can reduce nitrate conversion and nitric oxide availability.

This doesn’t mean you should stop practicing good oral hygiene. Brushing and cleaning between your teeth remain important for maintaining oral health.

Instead, if you’re specifically trying to support this pathway, it may be worth avoiding unnecessary use of strong antiseptic mouthwashes.

If you use a medicated mouthwash, follow your dentist’s or healthcare professional’s advice rather than stopping it on your own.

4. Eat Foods That Provide L-Arginine

Your body can also make nitric oxide from L-arginine, an amino acid found in a variety of foods.

Good dietary sources include:

  • Nuts
  • Seeds
  • Peanuts
  • Beans
  • Lentils
  • Soy foods
  • Whole grains
  • Some dairy products

L-arginine serves as a building block for nitric oxide production through enzymes called nitric oxide synthases.

But more L-arginine doesn’t necessarily mean more nitric oxide. Your body tightly regulates this pathway, and only a small proportion of dietary arginine is converted directly into nitric oxide.

A meta-analysis showed that longer-term consumption of tree nuts and peanuts improved fasting blood-vessel function. However, the researchers noted that the improvement could not be explained by their L-arginine content alone.

So rather than focusing on L-arginine alone, include these foods as part of an overall nutritious diet.

5. Include Foods Rich in L-Citrulline

L-citrulline is another amino acid that can help your body make nitric oxide.

And watermelon is one of its best-known food sources.

Here’s the interesting part: your body can convert L-citrulline into L-arginine, which is then used to produce nitric oxide. L-citrulline can also raise L-arginine levels more effectively than oral L-arginine because it is less extensively broken down during absorption.

Research on watermelon suggests it may support blood vessel function, arterial stiffness, and blood pressure, although results have varied, partly because the amount of L-citrulline in watermelon products can differ.

L-citrulline supplements have also been studied for blood flow, exercise performance, and recovery, but the findings are mixed.

So if you enjoy watermelon, it can be a simple, food-first way to add L-citrulline to your diet.

6. Get Some Sensible Sunlight

Sunlight may influence nitric oxide in a way that’s different from the nitrate pathway you get from foods.

Your skin contains nitrogen-containing compounds that can release nitric oxide when exposed to UVA radiation. In human studies, UVA exposure increased blood flow and temporarily lowered blood pressure, with the effects linked to the release of nitric oxide from the skin.

Sunlight may affect blood vessel function through a pathway that is independent of nitric oxide synthase and dietary nitrate availability.

However, this doesn’t mean you should deliberately expose your skin to large amounts of UV radiation to increase nitric oxide. Studies have produced mixed results, and researchers have not established UV exposure as a treatment for high blood pressure or cardiovascular disease.

For now, think of sunlight as an interesting area of nitric oxide research—not a reason to skip sun protection.

7. Include Cocoa and Dark Chocolate

Cocoa is another interesting food when it comes to nitric oxide and blood vessel health. Its flavanols, particularly epicatechin, may influence how well your blood vessels function.

In human research, flavanol-rich cocoa has been shown to increase nitric oxide-related compounds and improve flow-mediated dilation (FMD), a measure of how well blood vessels widen when blood flow increases.

More recent evidence points in the same direction. A 2026 meta-analysis found that cocoa flavanols improved FMD and pulse-wave velocity, although the certainty of evidence for these vascular outcomes was still limited.

So, how can you include cocoa? Unsweetened cocoa powder or dark chocolate with 70–85% cocoa content can be simple ways to add cocoa flavanols to your diet. Just remember that chocolate can still be calorie-dense, so more isn’t necessarily better.

8. Breathe Through Your Nose

Your nose plays a bigger role in nitric oxide than you might think.

The nasal passages and sinuses produce high levels of nitric oxide, with the sinuses acting as an important reservoir. When you breathe through your nose, some of this NO travels with the air into your lungs, where it may support airway function and local respiratory defenses.

In fact, human research has found that nasal breathing produces more exhaled NO than mouth breathing during exercise.

But don’t overstate the finding. Nasal breathing doesn’t necessarily increase your body’s overall nitric oxide production like dietary nitrate can. The strongest evidence concerns nasal NO and its role in the respiratory system.

9. Consider Nitric Oxide Supplements

If diet and lifestyle aren’t enough, you may come across supplements marketed as “nitric oxide boosters.” Despite the name, most don’t contain nitric oxide itself. Instead, they provide ingredients such as L-arginine, L-citrulline, or nitrate that can support the body’s nitric oxide pathways.

The research is promising, but supplements aren’t a guaranteed shortcut. L-arginine, for example, has been shown in a meta-analysis to reduce both systolic and diastolic blood pressure, although the effects varied between groups.

L-citrulline has also been studied for blood flow, blood pressure, exercise performance, and recovery, but the results are mixed.

Nitrate supplements, including concentrated beetroot products, have also been studied for their effects on nitric oxide availability and vascular function. But if you’re already eating plenty of nitrate-rich vegetables, a supplement may not be necessary.

And more isn’t always better. If you take medication that lowers blood pressure or affects blood-vessel dilation, talk with a healthcare professional before using these supplements, as some ingredients may further lower blood pressure.

The Bottom Line

You don’t need a nitric oxide supplement to support nitric oxide production.

Start with the basics: eat nitrate-rich vegetables, exercise regularly, maintain good oral health, and include foods rich in L-arginine and L-citrulline.

If you have high blood pressure, poor circulation, erectile difficulties, or another cardiovascular concern, talk with a healthcare professional rather than relying on nitric oxide supplements alone.

  1. Jones AM, Vanhatalo A, Seals DR, Rossman MJ, Piknova B, Jonvik KL. Dietary Nitrate and Nitric Oxide Metabolism: Mouth, Circulation, Skeletal Muscle, and Exercise Performance. Med Sci Sports Exerc. 2021 Feb 1;53(2):280-294. doi: 10.1249/MSS.0000000000002470. PMID: 32735111.
  2. Arefirad T, Seif E, Sepidarkish M, Mohammadian Khonsari N, Mousavifar SA, Yazdani S, Rahimi F, Einollahi F, Heshmati J, Qorbani M. Effect of exercise training on nitric oxide and nitrate/nitrite (NOx) production: A systematic review and meta-analysis. Front Physiol. 2022 Oct 4;13:953912. doi: 10.3389/fphys.2022.953912. PMID: 36267589; PMCID: PMC9576949.
  3. Bryan NS, Burleigh MC, Easton C. The oral microbiome, nitric oxide and exercise performance. Nitric Oxide. 2022 Aug 1;125-126:23-30. doi: 10.1016/j.niox.2022.05.004. Epub 2022 May 28. PMID: 35636654.
  4. Stuehr DJ. Enzymes of the L-arginine to nitric oxide pathway. J Nutr. 2004 Oct;134(10 Suppl):2748S-2751S; discussion 2765S-2767S. doi: 10.1093/jn/134.10.2748S. PMID: 15465779.
  5. Mariotti F, Petzke KJ, Bonnet D, Szezepanski I, Bos C, Huneau JF, Fouillet H. Kinetics of the utilization of dietary arginine for nitric oxide and urea synthesis: insight into the arginine-nitric oxide metabolic system in humans. Am J Clin Nutr. 2013 May;97(5):972-9. doi: 10.3945/ajcn.112.048025. Epub 2013 Mar 27. PMID: 23535108.
  6. Smeets ETHC, Mensink RP, Joris PJ. Effects of tree nut and groundnut consumption compared with those of l-arginine supplementation on fasting and postprandial flow-mediated vasodilation: Meta-analysis of human randomized controlled trials. Clin Nutr. 2021 Apr;40(4):1699-1710. doi: 10.1016/j.clnu.2020.09.015. Epub 2020 Sep 15. PMID: 32980186.
  7. Allerton TD, Proctor DN, Stephens JM, Dugas TR, Spielmann G, Irving BA. l-Citrulline Supplementation: Impact on Cardiometabolic Health. Nutrients. 2018 Jul 19;10(7):921. doi: 10.3390/nu10070921. PMID: 30029482; PMCID: PMC6073798.
  8. Volino-Souza M, Oliveira GV, Conte-Junior CA, Figueroa A, Alvares TS. Current Evidence of Watermelon (Citrullus lanatus) Ingestion on Vascular Health: A Food Science and Technology Perspective. Nutrients. 2022 Jul 15;14(14):2913. doi: 10.3390/nu14142913. PMID: 35889869; PMCID: PMC9318495.
  9. Gonzalez AM, Trexler ET. Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. J Strength Cond Res. 2020 May;34(5):1480-1495. doi: 10.1519/JSC.0000000000003426. PMID: 31977835.
  10. Opländer C, Volkmar CM, Paunel-Görgülü A, van Faassen EE, Heiss C, Kelm M, Halmer D, Mürtz M, Pallua N, Suschek CV. Whole body UVA irradiation lowers systemic blood pressure by release of nitric oxide from intracutaneous photolabile nitric oxide derivates. Circ Res. 2009 Nov 6;105(10):1031-40. doi: 10.1161/CIRCRESAHA.109.207019. Epub 2009 Sep 24. PMID: 19797169.
  11. Liu D, Fernandez BO, Hamilton A, Lang NN, Gallagher JMC, Newby DE, Feelisch M, Weller RB. UVA irradiation of human skin vasodilates arterial vasculature and lowers blood pressure independently of nitric oxide synthase. J Invest Dermatol. 2014 Jul;134(7):1839-1846. doi: 10.1038/jid.2014.27. Epub 2014 Jan 20. PMID: 24445737.
  12. Ghadjar P, Syzonenko N, Strzebinczyk AL, Arora S, Michel B, Scharr MV, Piazena H, Zips D, Seifert G. Effects of ultraviolet light exposure on blood pressure: a systematic review. Photochem Photobiol Sci. 2026 Aug 17. doi: 10.1007/s43630-026-00970-5. Epub ahead of print. PMID: 42606691.
  13. Schroeter H, Heiss C, Balzer J, Kleinbongard P, Keen CL, Hollenberg NK, Sies H, Kwik-Uribe C, Schmitz HH, Kelm M. (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1024-9. doi: 10.1073/pnas.0510168103. Epub 2006 Jan 17. PMID: 16418281; PMCID: PMC1327732.
  14. Sakuda M, Ito K, Adaniya Y, Watanabe N, Han L, Natsume M, Nakamura K. Impact of cocoa flavanols on blood pressure and vascular function: an updated systematic review and meta-analysis of randomized controlled trials. J Nutr Health Aging. 2026 Sep 1;30(11):100966. doi: 10.1016/j.jnha.2026.100966. Epub ahead of print. PMID: 42679502; PMCID: PMC13563239.
  15. Lundberg JO. Nitric oxide and the paranasal sinuses. Anat Rec (Hoboken). 2008 Nov;291(11):1479-84. doi: 10.1002/ar.20782. PMID: 18951492.
  16. Yasuda Y, Itoh T, Miyamura M, Nishino H. Comparison of exhaled nitric oxide and cardiorespiratory indices between nasal and oral breathing during submaximal exercise in humans. Jpn J Physiol. 1997 Oct;47(5):465-70. doi: 10.2170/jjphysiol.47.465. PMID: 9504133.
  17. Shiraseb F, Asbaghi O, Bagheri R, Wong A, Figueroa A, Mirzaei K. Effect of l-Arginine Supplementation on Blood Pressure in Adults: A Systematic Review and Dose-Response Meta-analysis of Randomized Clinical Trials. Adv Nutr. 2022 Aug 1;13(4):1226-1242. doi: 10.1093/advances/nmab155. PMID: 34967840; PMCID: PMC9340976.
  18. Gonzalez AM, Trexler ET. Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. J Strength Cond Res. 2020 May;34(5):1480-1495. doi: 10.1519/JSC.0000000000003426. PMID: 31977835.